You can learn Hormones, Vitamins and Enzymes roles in health
Note : After finishing this topic, please click Mark as Done.
This will ensure that your progress is recorded and the chapter is considered complete.
After completing this unit, You will be able to :
- explain the types Vitamins and its uses
- appreciate the hormones and its functions
- describe the role of enzymes
3. Enzymes
3.3. Diseases caused by enzyme deficiencies
Enzymes : Kirchoff first discovered enzyme in 1815. The term enzyme coined by Kuhne (1878). Enzyme may be defined as complex organic catalysts produced by the living cells for carrying out various reactions. Their action is highly specific i.e., a particular enzyme brings about a particular reaction only. Enzymes are proteins. Most active enzymes are associated with some non-protein component required for their activity. These are metal ions or smaller organic molecules called co-enzymes. The metal ions involved are Zn, Mg, Mn, Fe, Cu, K and Na.
Table : Diseases caused by enzyme deficiencies
|
Defective Enzyme |
Disease |
|
á-galactosidase |
Fabry disease |
|
tyrosinase |
Albinism |
|
beta-hexosaminidase A |
Tay-Sachs disease |
|
branched-chain ketoacid dehydrogenase complex |
Maple Syrup Urine disease |
|
cerebrosidase |
Gaucher disease Types I and II |
|
galactose-1-phosphate uridyl transferase |
Galactosemia |
|
phenylalanine hydroxylase |
Phenylketonuria (PKU) |
Source : Science and Technology, Dr BRAOU, HYD